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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLE
All Species:
18.48
Human Site:
S1896
Identified Species:
45.19
UniProt:
Q07864
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07864
NP_006222.2
2286
261518
S1896
Y
I
T
S
S
I
H
S
K
E
T
F
H
S
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543348
2273
260734
S1889
Y
I
T
S
S
I
H
S
K
E
I
F
H
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVF7
2283
262009
S1895
Y
I
T
N
S
I
H
S
K
E
I
F
H
S
L
Rat
Rattus norvegicus
NP_001100622
1515
174729
E1159
I
A
I
Q
S
S
W
E
L
C
R
L
T
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233985
2277
260654
S1891
Y
I
I
N
S
I
H
S
K
E
I
F
H
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121995
2284
262166
T1895
Y
I
T
N
S
I
H
T
K
E
I
F
H
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524462
2236
256683
I1876
I
Y
A
D
F
N
R
I
I
L
S
S
G
K
K
Honey Bee
Apis mellifera
XP_393171
2183
252634
W1827
Q
I
I
H
F
Y
R
W
L
R
S
P
N
A
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328167
2221
254636
A1857
F
E
L
T
A
A
K
A
Y
C
D
S
V
L
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21951
2222
255653
Y1860
A
L
G
S
T
I
V
Y
A
D
R
N
Q
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.7
N.A.
90.5
60.7
N.A.
N.A.
83.7
N.A.
80
N.A.
55.2
54.6
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
94.6
N.A.
95
63.5
N.A.
N.A.
92
N.A.
90.2
N.A.
71.9
71.5
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
86.6
13.3
N.A.
N.A.
80
N.A.
80
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
93.3
13.3
N.A.
N.A.
86.6
N.A.
93.3
N.A.
6.6
33.3
N.A.
N.A.
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
40.5
N.A.
Protein Similarity:
62.7
N.A.
N.A.
N.A.
60.1
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
10
10
0
10
10
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
10
0
50
0
0
0
0
10
% E
% Phe:
10
0
0
0
20
0
0
0
0
0
0
50
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
10
0
0
50
0
0
0
0
0
50
0
0
% H
% Ile:
20
60
30
0
0
60
0
10
10
0
40
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
0
50
0
0
0
0
10
20
% K
% Leu:
0
10
10
0
0
0
0
0
20
10
0
10
0
10
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
30
0
10
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
20
0
0
10
20
0
0
0
0
% R
% Ser:
0
0
0
30
60
10
0
40
0
0
20
20
0
60
0
% S
% Thr:
0
0
40
10
10
0
0
10
0
0
10
0
10
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% W
% Tyr:
50
10
0
0
0
10
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _